\u6982\u8981<\/strong><\/p>\n\n\n\n \u80be\u810f\u6709\u4ee5\u4e0b\u7684\u529f\u80fd:<\/p>\n\n\n\n \u72fc\u75ae\u80be\u708e<\/strong><\/p>\n\n\n\n \u5f53\u80be\u810f\u53d7\u5230\u75be\u75c5\u5f71\u54cd\u65f6\uff0c\u5176\u529f\u80fd\u5c31\u4f1a\u5931\u8c03\u3002\u7136\u800c\u80be\u810f\u672c\u8eab\u62e5\u6709\u6781\u5927\u7684\u540e\u5907\u529f\u80fd\uff1b\u80be\u810f\u75be\u75c5\u901a\u5e38\u5728\u5176\u521d\u671f\u65f6\u662f\u6ca1\u663e\u793a\u4ec0\u4e48\u75c7\u72b6\u7684\uff0c\u5176\u75c7\u72b6\u4e00\u76f4\u5230\u75be\u75c5\u7684\u665a\u671f\u624d\u4f1a\u663e\u9732\u3002<\/p>\n\n\n\n \u5bf9\u60a3\u4e0a\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u4eba\u6765\u8bf4\uff0c\u5927\u7ea6\u6709\u767e\u5206\u4e4b\u4e94\u5341\u5230\u767e\u5206\u4e4b\u516b\u5341\u7684\u60a3\u8005\u7684\u80be\u810f\u662f\u53ef\u80fd\u53d7\u5230\u5f71\u54cd\u7684\u3002\u5728\u5927\u591a\u6570\u7684\u4e2a\u6848\u5f53\u4e2d\uff0c\u60a3\u8005\u7684\u80be\u810f\u53ea\u662f\u53d7\u5230\u8f7b\u5fae\u7684\u5f71\u54cd\u800c\u4e0d\u6210\u4ec0\u4e48\u95ee\u9898\uff0c\u7136\u800c\uff0c\u4f1a\u6709\u4e9b\u60a3\u8005\u7684\u80be\u810f\u6240\u53d7\u7684\u5f71\u54cd\u5374\u8d8b\u4e25\u91cd\u3002\u4f46\u662f\uff0c\u5728\u8fc7\u53bb30\u523040\u5e74\u4ee5\u6765\uff0c\u6cbb\u7597\u7ecf\u5df2\u5927\u5927\u7684\u6539\u53d8\u4e86\u5bf9\u4e25\u91cd\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u9884\u540e-\u5373\u662f\u75be\u75c5\u7684\u53d1\u5c55\u8fc7\u7a0b\u4e0e\u6700\u540e\u7ed3\u679c\u7684\u9884\u6d4b\u3002\u73b0\u5728\uff0c\u6709\u4e86\u9002\u5f53\u7684\u6cbb\u7597\uff0c\u5f88\u591a\u4e25\u91cd\u72fc\u75ae\u80be\u708e\u7684\u60a3\u8005\u90fd\u6709\u4e86\u8d77\u8272\u5e76\u4e14\u80fd\u8fc7\u7740\u6b63\u5e38\u7684\u751f\u6d3b\u3002<\/p>\n\n\n\n \u5f53\u6709\u86cb\u767d\u6c89\u79ef\u5728\u80be\u810f\u7cbe\u5de7\u7684\u8fc7\u6ee4\u5668\u5b98\u4ee5\u53ca\u8f93\u9001\u8840\u6db2\u5230\u80be\u810f\u7684\u8840\u7ba1\u6709\u53d1\u708e\u65f6\u5c31\u4f1a\u4fc3\u6210\u72fc\u75ae\u80be\u708e\u3002\u8fd9\u5c31\u4f1a\u5bfc\u81f4\u5c3f\u4e2d\u6709\u7ea2\u8840\u7403\u548c\u86cb\u767d\uff0c\u8840\u538b\u4e5f\u4f1a\u5347\u9ad8\uff0c\u548c \uff08\u5728\u8f83\u4e3a\u4e25\u91cd\u7684\u4e2a\u6848\uff09\u901a\u5e38\u901a\u8fc7\u5c3f\u4e2d\u6392\u6cc4\u51fa\u6765\u7684\u5316\u5b66\u5e9f\u7269\u4f1a\u5806\u79ef\u5728\u8840\u6db2\u4e2d\u3002<\/p>\n\n\n\n \u4e0d\u50cf\u5173\u8282\uff0c\u76ae\u80a4\u6216\u8111\u90e8\u90a3\u6837\uff0c\u6d89\u53ca\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u80be\u810f\u5f80\u5f80\u662f\u4e0d\u5448\u73b0\u4efb\u4f55\u75c7\u72b6\u7684\uff0c\u4e00\u76f4\u5230\u80be\u810f\u53d7\u5230\u635f\u574f\u624d\u6709\u75c7\u72b6\u3002\u7136\u540e\u60a3\u8005\u5c31\u4f1a\u62b1\u6028\u4f53\u91cd\u589e\u52a0\u548c\u80bf\u80c0\uff0c\u5c24\u5176\u662f\u811a\u548c\u817f\u90e8\u3002\u533b\u751f\u79f0\u4e3a\u6db2\u4f53\u56e4\u79ef\u4f53\u5185\u6216\u6c34\u80bf\u6216\u80be\u810f\u7efc\u5408\u75c5\u75c7\u3002\u8fd9\u4e9b\u90fd\u662f\u4e3b\u8981\u6d89\u53ca\u80be\u810f\u7684\u6700\u666e\u904d\u75c7\u72b6\u3002\u6700\u53ef\u6015\u7684\u5e76\u53d1\u75c7\u662f\u80be\u810f\u529f\u80fd\u8870\u7aed\uff0c\u7136\u800c\u5f88\u5e86\u5e78\u7684\u8fd9\u5e76\u4e0d\u666e\u904d\u3002\u5f53\u80be\u810f\u529f\u80fd\u8870\u7aed\u65e5\u8d8b\u4e25\u91cd\u65f6\uff0c\u60a3\u8005\u53ef\u80fd\u62b1\u6028\u75b2\u7d2f\uff0c\u98df\u6b32\u4e0d\u632f\uff0c\u53cd\u80c3\u548c\u5455\u5410\u3002\u5982\u679c\u4e0d\u63a5\u53d7\u6cbb\u7597\uff0c\u5c31\u4f1a\u5bfc\u81f4\u60c5\u7eea\u7684\u6539\u53d8\uff0c\u62bd\u6410\u548c\u5176\u4ed6\u5a01\u80c1\u751f\u547d\u7684\u95ee\u9898\u3002<\/p>\n\n\n\n \u8bc4\u4f30\u80be\u810f\u7684\u635f\u5bb3<\/strong><\/p>\n\n\n\n \u53ca\u65e9\u53d1\u73b0\u80be\u810f\u635f\u5bb3\u662f\u6781\u5176\u91cd\u8981\u7684\u3002\u9274\u4e8e\u8fd9\u4e2a\u539f\u56e0\uff0c\u533b\u751f\u4f1a\u8981\u60a8\u7ecf\u5e38\u4f5c\u80be\u810f\u529f\u80fd\u5316\u9a8c \uff08\u7b80\u5355\u7684\u5c3f\u548c\u8840\u6db2\u5316\u9a8c\uff09\u3002\u5c3f\u5206\u89e3\u80fd\u5448\u73b0\u80be\u810f\u53d1\u708e\u7684\u5404\u79cd\u75c7\u5019\uff0c\u5982\u7ea2\u8840\u7403\u51dd\u5757\u6216\u6709\u8fc7\u5206\u7684\u86cb\u767d\u3002\u8981\u786e\u5b9a\u80be\u810f\u53d7\u635f\u7684\u7a0b\u5ea6\uff0c\u901a\u5e38\u8981\u6536\u96c624\u5c0f\u65f6\u7684\u5c3f\u6db2\u6837\u672c\u3002\u5047\u5982\u80be\u810f\u529f\u80fd\u53d7\u635f\uff0c\u8840\u6db2\u5316\u9a8c\u5c06\u63d0\u4f9b\u6709\u5173\u8840\u6db2\u91cc\u5e9f\u7269\u6c34\u5e73\u589e\u52a0\u7684\u8d44\u6599\u3002\u6297\u8131\u6c27\u6838\u7cd6\u6838\u9178 \uff08DNA\uff09,\u6297\u4f53\u7684\u6ef4\u5b9a\u5ea6\u548c\u8865\u4f53\uff08C3\u548cC4\uff09\u7684\u6c34\u5e73\u4e5f\u8981\u7ecf\u5e38\u8861\u91cf\uff0c\u56e0\u4e3a\u5b83\u4eec\u80fd\u534f\u52a9\u5bf9\u72fc\u75ae\u6d3b\u52a8\u4f5c\u8bc4\u4f30\u3002<\/p>\n\n\n\n \u80be\u6d3b\u7ec4\u7ec7\u5207\u7247\u68c0\u67e5<\/strong> \u67096\u5927\u7ea7\u522b\u7684\u72fc\u75ae\u80be\u708e\u662f\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u6240\u9274\u522b\u7684\uff08\u56fd\u9645\u80be\u810f\u5b66\u534f\u4f1a\u57282004\u5e74\u65f6\u4e5f\u6709\u4f5c\u5206\u7c7b\uff0c\u4f46\u662f\u5e76\u8fd8\u672a\u5e7f\u6cdb\u53d7\u63a5\u7eb3\u3002<\/p>\n\n\n\n \u5982\u4eca\uff0c\u75c5\u7406\u5b66\u5bb6\u4e5f\u5c06\u6d3b\u7ec6\u80de\u5207\u7247\u68c0\u67e5\u7684\u7ed3\u679c\u5206\u7c7b\u8bb0\u5f55\u4e3a\u201c\u6d3b\u8dc3\u201d \uff08\u663e\u793a\u6d3b\u6027\u53d1\u708e\uff09\u6216 \u201c\u6162\u6027\u201d\uff08\u663e\u793a\u75a4\u75d5\uff09\u3002\u8fd9\u4e9b\u5c06\u534f\u52a9\u51b3\u5b9a\u662f\u5426\u503c\u5f97\u5c55\u5f00\u79ef\u6781\u7684\u6cbb\u7597\u3002<\/p>\n\n\n\n \u6cbb\u7597<\/strong><\/p>\n\n\n\n \u80be\u810f\u53d7\u5230\u5f88\u8f7b\u5fae\u7684\u635f\u4f24\u53ef\u80fd\u4e0d\u9700\u8981\u6cbb\u7597\u3002\u4e00\u822c\u6027\u7684\u6cbb\u7597\u63aa\u65bd\u662f\u5bf9\u5176\u4ed6\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u60a3\u8005\u5b9e\u65bd\u7684\u3002\u5bf9\u60a3\u8005\u7684\u80be\u810f\u6709\u6d3b\u6027\u53d1\u708e\u7684\u6cbb\u7406\uff0c\u4e00\u822c\u4e0a\u8981\u8f83\u4e3a\u79ef\u6781\u4ee5\u4fbf\u8fc5\u901f\u63a7\u5236\u75c5\u60c5\u6076\u5316\u548c\u9884\u9632\u6c38\u4e45\u7684\u4f24\u5bb3\u3002\u6cbb\u7406\u8ba1\u5212\u662f\u4f9d\u636e\u80be\u810f\u6d3b\u7ec4\u7ec7\u5207\u7247\u68c0\u67e5\u7684\u7ed3\u679c\u6765\u51b3\u5b9a\u3002<\/p>\n\n\n\n \u7c7b\u56fa\u9187<\/strong><\/p>\n\n\n\n \u76ae\u8d28\u7c7b\u56fa\u9187 \uff08Corticosteroids\uff09 \u5982 \u75c9\u5316\u6ce2\u5c3c\u677e \uff08prednisolone\uff09<\/strong> \u8fd8\u662f\u4fdd\u7559\u4e3a\u6cbb\u7597\u72fc\u75ae\u80be\u708e\u7684\u4e3b\u8981\u836f\u7269\u3002\u5bf9\u4e25\u91cd\u7684\u4e2a\u6848\uff0c\u5b83\u53ef\u5f00\u59cb\u4ee5\u201c\u8109\u51b2\u201d\u7597\u6cd5\u6ce8\u5165\u9759\u8109\u3002\u5bf9\u4e0d\u592a\u4e25\u91cd\u7684\u4e2a\u6848\uff0c\u5374\u53ef\u4f5c\u53e3\u670d\u7c7b\u56fa\u9187\u7597\u6cd5\u3002\u6b64\u836f\u662f\u73b0\u6709\u6700\u4f73\u7684\u6297\u708e\u836f\u7269\uff1b\u5b83\u5bf9\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u60a3\u8005\u7684\u75c5\u60c5\u7684\u6539\u5584\u548c\u590d\u539f\u6709\u6781\u5927\u7684\u8d21\u732e\u3002<\/p>\n\n\n\n \u5f53\u60a3\u8005\u7684\u80be\u810f\u6709\u663e\u8457\u7684\u635f\u5bb3\u6216\u53ef\u80fd\u6076\u5316\u5230\u5a01\u80c1\u751f\u547d\u65f6\uff0c\u533b\u751f\u5c31\u4f1a\u5904\u65b9\u75c9\u5316\u6ce2\u5c3c\u677e \uff08Prednisolone \uff09\u3002\u533b\u751f\u4e00\u5411\u90fd\u5f88\u4e25\u8c28\u5904\u65b9\u8fd9\u79cd\u836f\u7269\u56e0\u4e3a\u5b83\u53ef\u5f15\u8d77\u79cd\u79cd\u7684\u526f\u4f5c\u7528\u3002\u4e00\u4e9b\u77ed\u671f\u7684\u526f\u4f5c\u7528\u662f\u98df\u6b32\u589e\u52a0\uff0c\u4f53\u91cd\u589e\u52a0\u548c\u6ee1\u6708\u8138\u3002\u957f\u671f\u7684\u5305\u62ec\u6709\u9aa8\u8d28\u758f\u677e\uff0c\u8840\u538b\u5347\u9ad8\u548c\u76ae\u80a4\u53d8\u8584\u3002<\/p>\n\n\n\n \u6709\u65f6\u60a3\u8005\u53ef\u80fd\u8bd5\u56fe\u505c\u6b62\u670d\u7528\u75c9\u5316\u6ce2\u5c3c\u677e \uff08prednisolone) \u6216\u51cf\u5c11\u5b83\u7684\u5242\u91cf\u3002\u4ed6\u4eec\u53ef\u80fd\u53d7\u591f\u4e86\u79cd\u79cd\u7684\u526f\u4f5c\u7528\u6216\u8005\u611f\u89c9\u5230\u75c5\u60c5\u6709\u6240\u597d\u8f6c\u6216\u6076\u5316\u3002\u5f88\u91cd\u8981\u7684\u4e00\u70b9\u5c31\u662f\u670d\u7528\u75c9\u5316\u6ce2\u5c3c\u677e \uff08prednisolone\uff09 \u7684\u60a3\u8005\u8981\u4e86\u89e3\u8fd9\u79cd\u836f\u7269\u7684\u4f5c\u7528\u4ee5\u53ca\u5728\u6ca1\u6709\u533b\u751f\u7684\u7763\u5bfc\u4e0b\u4e3a\u4ec0\u4e48\u505c\u6b62\u670d\u7528\u548c\u66f4\u6362\u836f\u7269\u662f\u90a3\u4e48\u7684\u5371\u9669\u3002<\/p>\n\n\n\n \u5176\u4ed6\u514d\u75ab\u6291\u5236\u836f\u7269<\/strong><\/p>\n\n\n\n \u5bf9\u6cbb\u7597\u6709\u5173\u72fc\u75ae\u80be\u708e\u7684\u4e00\u9879\u663e\u8457\u8fdb\u6b65\u5c31\u662f\u4f7f\u7528\u514d\u75ab\u6291\u5236\u836f\u7269\uff0c\u5c24\u5176\u662f\u73af\u78f7\u9170\u80fa \uff08cyclophosphamide\uff09<\/strong>. \u514d\u75ab\u6291\u5236\u836f\u7269\u80fd\u51cf\u5c11\u5bfc\u81f4\u53d1\u708e\u6297\u4f53\u7684\u751f\u4ea7\u3002<\/p>\n\n\n\n \u73af\u78f7\u9170\u80fa\uff0c\u901a\u5e38\u662f\u548c\u4e2d\u7b49\u5242\u91cf\u7684\u75c9\u5316\u6ce2\u5c3c\u677e (prednisolone) \u5904\u65b9\u7ed9\u8f83\u4e3a\u6d3b\u8dc3\u4e0e\u79ef\u6781\u7b49\u7ea7\u7684\u72fc\u75ae\u80be\u708e\u7684\u60a3\u8005\u3002\u5b83\u53ef\u53e3\u670d\u6216\u6ce8\u5165\u975c\u8108\u3002\u5bf9\u4e25\u91cd\u7684\u4e2a\u6848\uff0c\u5927\u5242\u91cf\u7684\u76ae\u8d28\u7c7b\u56fa\u9187 \uff08Corticosteroids\uff09 \u548c\u73af\u78f7\u9170\u80fa\uff0c\uff08cyclophosphamide\uff09 \u662f\u4ee5\u201c\u8109\u51b2\u201d\u7597\u6cd5\u6ce8\u5165\u9759\u8109\u3002\u6709\u5f88\u591a\u4e2a\u6848\u91c7\u7528\u4e86\u8fd9\u79cd\u7597\u6cd5\u4e4b\u540e\uff0c\u5bf9\u6d6a\u75ae\u80be\u708e\u75be\u75c5\u5df2\u6709\u4e86\u663e\u8457\u7684\u6539\u5584\uff1b\u5bf9\u6d3b\u7ec4\u7ec7\u5207\u7247\u68c0\u67e5\u7684\u6837\u672c\u89c2\u5bdf\u6709\u4e86\u6539\u8fdb\uff1b\u5c3f\u6db2\u91cc\u7684\u86cb\u767d\u542b\u91cf\u6709\u4e86\u51cf\u4f4e\u4ee5\u53ca\u80be\u810f\u529f\u80fd\u6709\u4e86\u6539\u5584\u3002<\/p>\n\n\n\n \u73af\u78f7\u9170\u80fa\uff0c\u4e5f\u6709\u5f88\u591a\u526f\u4f5c\u7528\u3002\u8fd9\u5305\u62ec\u767d\u8840\u7403\u7684\u51cf\u5c11\u800c\u4f7f\u60a3\u8005\u66f4\u5bb9\u6613\u53d7\u5230\u7ec6\u83cc\u548c\u5176\u4ed6\u7684\u611f\u67d3\u3002\u5b83\u4e5f\u80fd\u4fc3\u4f7f\u8180\u5149\u6d41\u8840\uff08\u51fa\u8840\u8180\u80f1\u708e \uff09\uff0c\u8131\u53d1\uff0c\u5973\u60a3\u8005\u7684\u5375\u5de2\u4e0d\u80fd\u6b63\u5e38\u751f\u7522\u8377\u5c14\u8499\uff08\u5375\u5de2\u529f\u80fd\u5931\u8abf\uff09\u548c\u7537\u60a3\u8005\u7684\u7cbe\u5b50\u51cf\u5c11\u3002\u957f\u671f\u6765\u8bf4 \uff0c\u5bf9\u60a3\u4e0a\u67d0\u79cd\u764c\u75c7\u7684\u98ce\u9669\u4e5f\u4f1a\u7a0d\u4e3a\u63d0\u9ad8\u3002\u56e0\u6b64\u7ecf\u5e38\u505a\u8840\u6db2\u5316\u9a8c\u662f\u5fc5\u8981\u7684\uff0c\u800c\u60a3\u8005\u4e5f\u8981\u7ecf\u5e38\u770b\u4ed6\u4eec\u7684\u533b\u751f\u3002<\/p>\n\n\n\n \u54aa\u5511\u7409\u8198\u5464 \uff08Azathioprine\uff09<\/strong>– \u79fb\u62a4\u5b81 (Imuran) \u4e5f\u6709\u65f6\u548c\u75d9\u5316\u6ce2\u5c3c\u677e \uff08prednisolone) \u7ed3\u5408\u4f7f\u7528\uff0c\u4f5c\u4e3a\u7c7b\u56fa\u9187\u8f85\u4f50\u836f\u7269\uff0c\u5b83\u901a\u5e38\u7528\u6765\u6291\u5236\u514d\u75ab\u53cd\u5e94\u4f5c\u7528\uff0c\u53ef\u5e2e\u52a9\u5ef6\u7f13\u75c5\u60c5\u7684\u6076\u5316\uff0c\u51cf\u5c11\u5bf9\u7c7b\u56fa\u9187\u7684\u9700\u6c42\u3002\u4f46\u662f\uff0c\u5b83\u7684\u5e94\u7528\u5e76\u4e0d\u6bd4\u73af\u78f7\u9170\u80fa\uff0c\u90a3\u4e48\u6d41\u884c,\u56e0\u4e3a\u5b83\u5728\u5bf9\u4e25\u91cd\u72fc\u75ae\u80be\u708e\u7684\u590d\u539f\u6bd4\u8f83\u6ca1\u6709\u90a3\u4e48\u6709\u6548\u3002<\/p>\n\n\n\n \u6cbb\u7642\u4e25\u91cd\u72fc\u75ae\u80be\u708e\u7684\u5176\u4ed6\u6bd4\u8f03\u65b0\u548c\u6bd2\u6027\u8f83\u8f7b\u7684\u514d\u75ab\u6291\u5236\u836f\u7269\u5305\u62ec\u6709 mycophenolate (Cell-Cept, Mifortic), tacrolimus (Prograf), \u548c rituximab (Mathera) \u7b49\u3002<\/p>\n\n\n\n \u5229\u5c3f\u5242\u548c\u6297\u9ad8\u8840\u538b\u4e2d\u4ecb<\/strong> 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\uff09\u3002<\/p>\n\n\n\n \u9002\u5f53\u7684\u6cbb\u7597\uff0c\u4e00\u822c\u4e0a\u5bf9\u72fc\u75ae\u80be\u708e\u90fd\u6709\u826f\u597d\u7684\u7ed3\u679c\u3002 \u5982\u679c\u4e0d\u5e78\u6709\u80be\u810f\u8870\u7aed\uff0c\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u6d3b\u52a8\u901a\u5e38\u4f1a\u6d88\u5931\u3002\u8fdb\u884c\u4e86\u6362\u80be\u548c\u6d17\u80be\u4e4b\u540e\uff0c\u60a3\u8005\u53ef\u4ee5\u4fdd\u6301\u6709\u610f\u4e49\u7684\u751f\u6d3b\u3002\u7814\u7a76\u5458\u5411\u6765\u5bf9\u72fc\u75ae\u80be\u708e\u7684\u7814\u7a76\u6709\u6781\u5927\u7684\u5174\u8da3\uff1b\u5f53\u5bf9\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u6709\u4e86\u8fdb\u4e00\u6b65\u7684\u4e86\u89e3\u4e4b\u540e\uff0c\u76f8\u4fe1\u52bf\u5fc5\u4f1a\u66f4\u8fdb\u4e00\u6b65\u6539\u5584\u8fd9\u79cd\u75be\u75c5\u7684\u6cbb\u7406\u3002<\/p>\n","protected":false},"excerpt":{"rendered":" \u6982\u8981 \u80be\u810f\u6709\u4ee5\u4e0b\u7684\u529f\u80fd: \u72fc\u75ae\u80be\u708e 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